Brain blood vessels health: What is the influence of atrial fibrillation, high blood pressure and age?

Atrial fibrillation is one of the most common forms of abnormal heart rhythm and its incidence increases with age. Atrial fibrillation is associated with increased risk of stroke, cognitive decline and dementia. Our research seeks to better understand the precise mechanisms for this. We believe an important potential contributing factor is that the ability of brain blood vessels to tightly control their blood flow is impaired as a result of atrial fibrillation.

We are currently inviting three groups of men and women aged over 50 years to participate, with a particular focus on the third group (healthy individuals).

  1. Patients with atrial fibrillation
  2. Patients with normal heart rhythm but high blood pressure
  3. Healthy individuals with normal heart rhythm and normal blood pressure

Anyone expressing an initial interest in participating is provided with comprehensive study information documents and a follow-up call is scheduled to check the eligibility to participate. The study involves a single experimental visit lasting one morning that will be conducted at the University of Birmingham Institute of Cardiovascular Sciences at City Hospital. Travel to the hospital and parking charges will be reimbursed. The study includes a small blood sample, the completion of some questionnaires/quizzes, and the monitoring of your brain blood flow, breathing, and blood pressure.

If you would like to receive further information or have any questions regarding the study, please contact Dr Rehan Junejo on or Dr James Fisher on or on 0121 414 8011.

Read the Participant Information Sheet